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London: Compared to individuals with blood type O, women with blood
groups A, B and AB are at higher risk of developing Type 2 diabetes, a
study has found.
"Our findings support a strong relationship between blood group and
diabetes risk, with participants with the O blood type having a lower
risk of developing Type 2 diabetes," said Guy Fagherazzi from Centre
for Research in Epidemiology and Population Health in France.
For the study, the researchers collected data from more than 80,000
women in France followed between 1990 and 2008.
The results showed that, compared to women with group O blood, women
with group A were 10 percent more likely to develop Type 2 diabetes
and those with group B 21 percent more likely.
The AB group was 17 percent more likely to develop Type 2 diabetes.
Compared with O- women, the highest increased risk of developing Type
2 diabetes was found in B+ (35 percent increased risk), followed by
AB+ (26 percent), A- (22 percent), A+ (17 percent).
"The present study shows for the first time in a large prospective
cohort that specific ABO blood groups are associated with an increased
Type 2 diabetes risk," Fagherazzi said.
The authors say that the reasons behind the association are currently
unknown, but could be related to a number of factors.
It has been suggested that the human ABO locus might influence
endothelial or inflammation markers.
ABO grouping is also associated with various molecules known to be
connected to Type 2 diabetes.
The study was published in the journal Diabetologia.
Credit: IANS
