How pepper is good for your gut revealed

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Washington: A new study has revealed that pepper reduces the risk of

colorectal tumors. According to the study by researchers at the

University of California, San Diego School of Medicine, the active

ingredient in chili peppers – produces chronic activation of a

receptor on cells lining the intestines of mice, triggering a reaction

that ultimately reduces the risk of colorectal tumors. The receptor or

ion channel, called TRPV1, was originally discovered in sensory

neurons, where it acts as a sentinel for heat, acidity and spicy

chemicals in the environment. Eyal Raz said that these are all

potentially harmful stimuli to cells, thus TRPV1 was quickly described

as a molecular 'pain receptor.' This can be considered to be its

conventional function, which all takes place in the nervous system.

The scientists discovered that TRPV1, once activated by the EGFR,

initiates a direct negative feedback on the EGFR, dampening the latter

to reduce the risk of unwanted growth and intestinal tumor

development. They found that mice genetically modified to be TRPV1-

deficient suffered higher- than-normal rates of intestinal tumor

growths. The study was published in The Journal of Clinical



Kofi Oppong Kyekyeku

I am a Ghanaian Broadcast Journalist/Writer who has an interest in General News, Sports, Entertainment, Health, Lifestyle and many more.

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